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Chemotherapy Drugs: Dactinomycin (actinomycin D, Cosmegen)

Dactinomycin (actinomycin D, Cosmegen)

Discover out what dactinomycin is, how you’ve gotten it and different vital details about having dactinomycin.

Dactinomycin is a cancer treatment and can be recognized by its model identify, Cosmegen.

It’s a treatment for a number of several types of cancer.

The way it works

Dactinomycin works by damaging cancer cells’ DNA. When DNA is broken, a cell can not divide into 2 new cells, so this helps to cease the cancer rising.

How you’ve got it

You may have dactinomycin into your bloodstream (intravenously). It’s a yellow liquid.

Medication into your bloodstream

You might have the treatment via a drip into your arm. A nurse places a small tube (a cannula) into one in all your veins and connects the drip to it.

You would possibly want a central line. This can be a lengthy plastic tube that offers the medication into a big vein, both in your chest or via a vein in your arm. It stays in when you’re having treatment, which can be for a couple of months.

When you’ve it

The treatment plan for dactinomycin is determined by the kind of cancer you might have. You may need it together with different medicine. Your physician or nurse may give you details about your treatment.

Assessments throughout treatment

You’ve got blood assessments earlier than beginning treatment and through your treatment. They verify your ranges of blood cells and different substances within the blood. Additionally they examine how effectively your liver and kidneys are working.

Unwanted effects

Essential data

Different medicines, meals and drink

Cancer medication can work together with another medicines and natural merchandise. Inform your physician or pharmacist about any medicines you’re taking. This consists of nutritional vitamins, natural dietary supplements and over-the-counter cures.

Being pregnant and contraception

This treatment may hurt a child growing within the womb. It is crucial to not change into pregnant or father a toddler if you are having treatment and for a couple of months afterwards. Discuss to your physician or nurse about efficient contraception and for the way lengthy it is best to use it earlier than beginning treatment.

Lack of fertility

We don’t understand how this treatment may have an effect on fertility. You might not be capable of grow to be pregnant or father a baby after treatment with this drug. Discuss to your physician earlier than beginning treatment if you happen to assume it’s possible you’ll need to have a child sooner or later.

Some males may be capable to retailer sperm earlier than beginning treatment. Some girls would possibly have the ability to retailer eggs or embryos earlier than treatment.



Don’t breastfeed throughout this treatment as a result of the drug could come via in your breast milk.

Treatment for different situations

At all times inform different docs, nurses, pharmacists or dentists that you just’re having this treatment for those who want treatment for anything, together with enamel issues.


Don’t have immunisations with stay vaccines whilst you’re having treatment and for a minimum of 6 months afterwards.

Within the UK, reside vaccines embrace rubella, mumps, measles, BCG, yellow fever and shingles vaccine (Zostavax).

You possibly can:

  • produce other vaccines, however they may not offer you as a lot safety as standard
  • have the flu vaccine
  • keep up a correspondence with different individuals who’ve had stay vaccines as injections

Keep away from contact with individuals who’ve had stay vaccines taken by mouth (oral vaccines). This contains the rotavirus vaccine given to infants. The virus is within the child’s urine for as much as 2 weeks and may make you ailing. So, keep away from altering their nappies for two weeks after their vaccination if attainable. Or put on disposable gloves and wash your arms nicely afterwards.

You additionally have to keep away from anybody who has had oral polio or typhoid vaccination lately.

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