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Chemotherapy Drugs: Nab-paclitaxel (Abraxane)

Nab-paclitaxel (Abraxane)

Discover out what nab-paclitaxel is, how you may have it and different vital details about having nab-paclitaxel.

Nab-paclitaxel is a chemotherapy drug and can also be recognized by its model identify, Abraxane. It combines the chemotherapy drug paclitaxel with a protein referred to as albumin.

It’s a treatment for:

  • breast cancer that has unfold
  • pancreatic cancer that has unfold
  • non small cell lung cancer

You normally have it if in case you have had an allergic response to paclitaxel.

The way it works

It really works by stopping cancer cells separating into two new cells, so it blocks the expansion of the cancer.

How you’ve it

You might have nab-paclitaxel as a drip into your bloodstream (intravenously) which lasts about 30 minutes.

Medicine into your bloodstream

You’ve got the treatment by means of a drip into your arm. A nurse places a small tube (a cannula) into certainly one of your veins and connects the drip to it.

You may want a central line. It is a lengthy plastic tube that offers the medicine into a big vein, both in your chest or by way of a vein in your arm. It stays in whilst you’re having treatment, which can be for just a few months.

When you may have it

Relying in your sort of cancer you might need nab-paclitaxel treatment each three weeks. Otherwise you may need it as soon as every week for three weeks after which have a relaxation from treatment for every week.

Checks throughout treatment

You might have blood exams earlier than beginning treatment and through your treatment. They examine your ranges of blood cells and different substances within the blood. Additionally they examine how effectively your liver and kidneys are working.

Unintended effects

Necessary data

Different medicines, meals and drink

Cancer medication can work together with another medicines and natural merchandise. Inform your physician or pharmacist about any medicines you’re taking. This contains nutritional vitamins, natural dietary supplements and over-the-counter cures.

This drug accommodates sodium (salt). You may have to take account of this if you’re on a managed sodium weight loss plan. Inform your physician if you’re on a low salt eating regimen.

Being pregnant and contraception

This drug might hurt a child creating within the womb. It is crucial to not turn out to be pregnant or father a toddler when you are having treatment with this drug and for at the very least 6 months afterwards. Discuss to your physician or nurse about efficient contraception earlier than beginning treatment.


It’s possible you’ll not be capable of change into pregnant or father a baby after treatment with this drug. Speak to your physician earlier than beginning treatment when you suppose you might need to have a child sooner or later. Males might be able to retailer sperm earlier than beginning treatment. Girls could possibly retailer eggs or ovarian tissue however that is uncommon.


Don’t breastfeed throughout this treatment as a result of the drug might come by means of in your breast milk.

Treatment for different situations

All the time inform different docs, nurses or dentists that you just’re having this drug in case you want treatment for the rest, together with tooth issues.


Don’t have immunisations with reside vaccines whilst you’re having treatment and for at the least 6 months afterwards.

Within the UK, reside vaccines embody rubella, mumps, measles, BCG, yellow fever and shingles vaccine (Zostavax).

You may:

  • produce other vaccines, however they won’t offer you as a lot safety as standard
  • have the flu vaccine
  • keep in touch with different individuals who’ve had stay vaccines as injections

Keep away from contact with individuals who’ve had stay vaccines taken by mouth (oral vaccines). This contains the rotavirus vaccine given to infants. The virus is within the child’s urine for as much as 2 weeks and may make you in poor health. So, keep away from altering their nappies for two weeks after their vaccination if doable. Or put on disposable gloves and wash your palms properly afterwards.

You additionally must keep away from anybody who has had oral polio or typhoid vaccination just lately.

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